Cellular Matrix®
Class III CE certified
Medical Devices
What is Cellular Matrix®?
Cellular Matrix® tubes allow the preparation of autologous platelet-rich plasma (RegenPRP®) combined with a non-crosslinked hyaluronic acid (HA) in a closed-circuit system. CM-PRP-HA has an excellent safety profile in clinical practice.
Cellular Matrix® technology combines the complementary clinical effects of RegenPRP® and hyaluronic acid (HA), giving better and longer-lasting results in patients with osteoarthritis.
Hyaluronic Acid
Hyaluronic acid is a major component of synovial fluid contributing to joint homeostasis.
25 years of clinical experience shows pain relief and functional improvement lasting 6 to 12 months in OA patients.
Plays a major role in viscosupplementation and pain relief in OA.5.
The network of HA chains generates an ideal cell-friendly matrix when combined with PRP.6.
Hyaluronic acid improves the activity of several molecules contained in platelet-rich plasma to provide additional benefits to OA patients.
Technology platform for standardized autologous regenerative medicine
The simple, safe and efficient point-of-care preparation of autologous platelet-rich plasma.
Blood Collection
Centrifugation
Resuspension
Resuspended
Ready to use
Technology Advantages
- User-independent standardized preparation.
- Minimum volume of blood required.
- Safe closed-circuit system.
- Mechanical isolation of PRP using a biologically inert gel after a 5-minute centrifugation.
- Reversible anticoagulation with a pharmaceutical grade solution of sodium citrate at pH 7.
- Minimal learning curve and ease of use.
- Operationally and clinically efficient process.
- Facilitates and streamlines routine practice.
CELLULAR MATRIX PLATFORM
- Certified technology for the preparation of RegenPRP® combined with hyaluronic acid (HA) (CM-PRP-HA).
- Contains 2 ml of non-crosslinked HA at a concentration of 20 mg/ml (40 mg total).
- HA produced by bacterial fermentation, thus free of animal proteins.
Scientific Advantages
- Demonstrated safety and efficacy.
- Evidence-based outcomes for numerous therapeutic indications.
- Large number of clinical studies, with over 200 publications.
Biological Advantages
- RegenPRP® is standardized, leucocyte reduced and easily reproducible Regen Lab specific separating gel technology guarantees minimal variability.
- Platelet recovery > 80%.
- High platelet quality Viable & functional platelets.
- Full plasma recovery No loss of plasma growth factors and fibrinogen.
- Leucocyte reduced PRP Depletion ~ 96.7% of pro-inflammatory granulocytes, leaving mainly lymphocytes and monocytes.
- Virtually no red blood cells Depletion of ~ 99.7% of erythrocytes.
RegenPRP® standardized performance
RegenBCT® Tube Properties
Blood Sample Vol Per Tube
4 ml.
Granulocyte Depletion
> 70 %
PRP Vol Per Tube
~2 ml of PRP combined with 2 ml of HA
Red Blood Cell Depletion
99.5 %
Platelet Recovery
> 70 %