Cellular Matrix®

Class III CE certified
Medical Devices

What is Cellular Matrix®?


Cellular Matrix® tubes allow the preparation of autologous platelet-rich plasma (RegenPRP®) combined with a non-crosslinked hyaluronic acid (HA) in a closed-circuit system. CM-PRP-HA has an excellent safety profile in clinical practice.

Cellular Matrix® technology combines the complementary clinical effects of RegenPRP® and hyaluronic acid (HA), giving better and longer-lasting results in patients with osteoarthritis.

Hyaluronic Acid

Hyaluronic acid is a major component of synovial fluid contributing to joint homeostasis.

  • 25 years of clinical experience shows pain relief and functional improvement lasting 6 to 12 months in OA patients. 

  • Plays a major role in viscosupplementation and pain relief in OA.5. 

  • The network of HA chains generates an ideal cell-friendly matrix when combined with PRP.6. 

Hyaluronic acid improves the activity of several molecules contained in platelet-rich plasma to provide additional benefits to OA patients.

Technology platform for standardized autologous regenerative medicine

The simple, safe and efficient point-of-care preparation of autologous platelet-rich plasma.

Blood Collection




Ready to use

Technology Advantages

  • User-independent standardized preparation.
  • Minimum volume of blood required.
  • Safe closed-circuit system.
  • Mechanical isolation of PRP using a biologically inert gel after a 5-minute centrifugation.
  • Reversible anticoagulation with a pharmaceutical grade solution of sodium citrate at pH 7.
  • Minimal learning curve and ease of use.
  • Operationally and clinically efficient process.
  • Facilitates and streamlines routine practice.


  • Certified technology for the preparation of RegenPRP® combined with hyaluronic acid (HA) (CM-PRP-HA).
  • Contains 2 ml of non-crosslinked HA at a concentration of 20 mg/ml (40 mg total).
  • HA produced by bacterial fermentation, thus free of animal proteins.

Scientific Advantages

  • Demonstrated safety and efficacy.
  • Evidence-based outcomes for numerous therapeutic indications.
  • Large number of clinical studies, with over 200 publications.

Biological Advantages

  • RegenPRP® is standardized, leucocyte reduced and easily reproducible Regen Lab specific separating gel technology guarantees minimal variability.
  • Platelet recovery > 80%.
  • High platelet quality Viable & functional platelets.
  • Full plasma recovery No loss of plasma growth factors and fibrinogen.
  • Leucocyte reduced PRP Depletion ~ 96.7% of pro-inflammatory granulocytes, leaving mainly lymphocytes and monocytes.
  • Virtually no red blood cells Depletion of ~ 99.7% of erythrocytes.

RegenPRP® standardized performance

Regen Lab devices use a separating gel technology that separates the plasma and platelets from the blood cells to produce RegenPRP with a standardized composition:

RegenBCT® Tube Properties

Blood Sample Vol Per Tube​

4 ml.

Granulocyte Depletion

> 70 %

PRP Vol Per Tube

~2 ml of PRP combined with 2 ml of HA

Red Blood Cell Depletion

99.5 %

Platelet Recovery​

> 70 %

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